Author

Xiumin Chen

The University of QueenslandORCID 0000-0002-5764-6705Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:electronic health records· 3 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Roger A. NicolliD· 3 shared Jing ZhouiD· 2 shared Joseph W. LynchiD· 2 shared Samuel J. PleasureiD· 2 shared Angelo KeramidasiD· 1 shared Argel Estrada‐MondragóniD· 1 shared Ariele L. GreenfieldiD· 1 shared Baouyen T. TraniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersNeuroscience

Roger A. NicollORCID

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5 papers

Recent·Most cited

NMDA receptor-dependent presynaptic homeostatic plasticity?

tianli dou, Junting Zhang, yidan hong, Xiumin Chen, Roger A. Nicoll

The paper investigates presynaptic homeostatic plasticity (PHP) in CA1 hippocampal synapses and finds no evidence for its occurrence.

bioRxiv · Mar 3, 2026 · PreprintNeuroscience

Disrupted callosal connectivity underlies long-lasting sensory-motor deficits in an NMDA receptor antibody encephalitis mouse model

Jing Zhou, Ariele L. Greenfield, Rita P. Loudermilk, Christopher M. Bartley, Chun Chen, Xiumin Chen, Morgane Leroux, Yujun Lu, Deanna Necula, Thomas T. Ngo, Baouyen T. Tran, Patrick S. Honma, Kelli Lauderdale, Chao Zhao, Xiaoyuan Zhou, , Samuel J. Pleasure

This study shows that exposure to anti-GluN1 mAb during development causes long-term sensory-motor deficits and callosal axon changes in mice.

Journal of Clinical Investigation · Dec 31, 2024Peer-reviewedNeuroscience

CaMKII autophosphorylation but not downstream kinase activity is required for synaptic memory

Xiumin Chen, Qixu Cai, Jing Zhou, Samuel J. Pleasure, Howard Schulman, Mingjie Zhang, Roger A. Nicoll

This study identifies that CaMKII autophosphorylation and binding to GluN2B are necessary for synaptic memory, while kinase activity is not required.

bioRxiv · Aug 25, 2023 · PreprintNeuroscience

Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit

Xuan Ling Hilary Yong, Lingrui Zhang, Liming Yang, Xiumin Chen, Jing Zhi Anson Tan, Xiaojun Yu, Mintu Chandra, Emma K. Livingstone, Jocelyn Widagdo, Marta Mota Vieira, Katherine W. Roche, Joseph W. Lynch, Angelo Keramidas, Brett M. Collins, Victor Anggono

This study identifies CaMKIIα-mediated phosphorylation of GluN2A at Ser-1459 as a mechanism regulating NMDAR trafficking and gating, with implications for epilepsy.

Cell Reports · Jul 1, 2021Peer-reviewedNeuroscience

Phosphorylation of the alpha2 glycine receptor induces an extracellular conformational change and slows the rise and decay rates of glycinergic synaptic currents

Sharifun Islam, Xiumin Chen, Argel Estrada‐Mondragón, Joseph W. Lynch

This study shows that phosphorylation of the 2 glycine receptor at S341 induces a conformational change and alters the kinetics of glycinergic synaptic currents.

bioRxiv · Oct 3, 2018 · PreprintNeuroscience