Author

Xin Ke

Tsinghua UniversityORCID 0000-0002-5860-5366Unclaimed ORCID profile · follow to get notified of new preprints

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Xin Ke1 paper · Inner Mongolia University

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2

Frequent Co-Authors

Desiree‐Faye Kaixin Toh· 2 shared Gang CheniD· 2 shared Hongwei WangiD· 2 shared Kiran M. PatiliD· 2 shared Manchugondanahalli S. KrishnaiD· 2 shared Rongguang LuiD· 2 shared Ruiyu Lin· 2 shared Xuan ZhaniD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Desiree‐Faye Kaixin Toh

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2 papers

Recent·Most cited

A new dual-affinity peptide nucleic acid for targeting miRNA-21 precursor rescues tumor repressor PTEN expression

Yun Lian, Anni Wang, Ruiyu Lin, Xin Ke, Xuan Zhan, Rongguang Lu, Tingli Qian, Arpita Ghosh, Alan Ann Lark Ong, Desiree‐Faye Kaixin Toh, Kiran M. Patil, Manchugondanahalli S. Krishna, Clément Dezanet, Jean‐Luc Décout, Souvik Maiti, , Gang Chen

This paper introduces a dual-affinity PNA (daPNA) platform that targets miR-21 precursor, inhibits Dicer activity, and rescues PTEN expression by blocking miR-21 maturation.

Cell Reports Physical Science · Nov 1, 2025Peer-reviewedMolecular Biology

Recognition of RNA secondary structures with a programmable peptide nucleic acid-based platform

Rongguang Lu, Liping Deng, Yun Lian, Xin Ke, Lixia Yang, Kun Xi, Alan Ann Lerk Ong, Yanyu Chen, Hanting Zhou, Zhenyu Meng, Ruiyu Lin, Shijian Fan, Yining Liu, Desiree‐Faye Kaixin Toh, Xuan Zhan, , Gang Chen

This paper introduces daPNAs, a programmable platform combining dbPNAs and asPNAs to target RNA junctions, demonstrating their use in inhibiting Dicer and regulating ribosomal frameshifting.

Cell Reports Physical Science · Aug 12, 2024Peer-reviewedBiochemistry