Jan Willem de Gee

Change-point oddball elicits pupil-linked signatures of Bayesian belief updating

This study uses a passive auditory oddball protocol to measure pupil-linked signatures of Bayesian belief updating during environmental change.

Task-irrelevant stimuli boost phasic pupil-linked arousal but not memory formation

The paper investigates whether task-irrelevant sounds affect memory formation and finds they boost pupil-linked arousal but not memory success.

Baseline activity of V1 interneurons connects pupil-linked arousal to engaged behavioral state

The paper shows that baseline activity of V1 interneurons mediates the relationship between pupil-linked arousal and engaged behavioral state in mice and humans.

Catecholamines reduce choice history biases in perceptual decision making

This study shows that catecholamines reduce choice history biases in perceptual decisions by affecting sensory evidence accumulation.

Adaptive arousal regulation: Pharmacologically shifting the peak of the Yerkes-Dodson curve by catecholaminergic enhancement of arousal

This study pharmacologically manipulates arousal in humans to test its impact on performance, finding that catecholaminergic enhancement shifts the arousal-performance curve while cholinergic agents do not.

Task-irrelevant stimuli reliably boost phasic pupil-linked arousal but do not affect decision formation

This study investigates whether task-irrelevant auditory stimuli can manipulate central arousal during decision-making, finding they affect pupil responses but not decision formation.

Strategic stabilization of arousal boosts sustained attention

The paper investigates how arousal and task utility interact to influence sustained attention in mice, finding that arousal stabilizes near optimal levels during high task utility.

A disinhibitory circuit mechanism explains a general principle of peak performance during mid-level arousal

The paper provides evidence for the inverted U-shaped relationship between arousal and performance in perceptual decision-making and presents a neurobiological model explaining it.

Catecholaminergic neuromodulation and selective attention jointly shape perceptual decision-making

This study investigates how catecholaminergic neuromodulation and spatial attention jointly influence perceptual decision-making through behavioral, algorithmic, and neural measures.

Brainstem fMRI signaling of surprise across different types of deviant stimuli

This study uses fMRI and pupillometry to show that both types of deviant stimuli activate multiple subcortical systems, including the locus coeruleus, in a 'local-global' paradigm.

Auditory accessory stimulus boosts pupil-linked arousal and reduces choice bias

The paper uses an auditory accessory stimulus to show that increased pupil-linked phasic arousal reduces choice bias without affecting response caution.

Goal-directed motor actions drive acetylcholine dynamics in sensory cortex

This study shows that acetylcholine dynamics in sensory cortex are driven by goal-directed motor actions rather than sensory cues or rewards during task learning.

Graded recruitment of pupil-linked neuromodulation by parametric stimulation of the vagus nerve

This study uses pupil dilation as a biosensor to assess real-time effects of vagus nerve stimulation on brain state in mice.

Pupil dilation and the slow wave ERP reflect surprise about choice outcome resulting from intrinsic variability in decision confidence

The paper shows that pupil dilation and slow wave ERP reflect surprise during decision-making under uncertainty, and that these signals are independent and depend on feedback awareness.

Phasic arousal suppresses biases in mice and humans across domains of decision-making

This study shows that phasic arousal suppresses decision biases in both mice and humans across different decision-making domains and sensory systems.

Comparing fMRI responses measured at 3 versus 7 Tesla across human cortex, striatum, and brainstem

This study compares 7 T and 3 T fMRI responses in human brain regions during a decision-making task, finding greater 7 T benefits in subcortical areas like the brainstem.

Choice history biases subsequent evidence accumulation

The paper shows that choice history biases perceptual decisions by altering evidence accumulation rather than shifting the starting point of accumulation.

Humans strategically shift decision bias by flexibly adjusting sensory evidence accumulation

The paper shows humans adjust decision bias by altering sensory evidence accumulation rates and cortical activity patterns in response to reward contingencies.

Task-evoked pupil responses reflect internal belief states

The paper shows that pupil responses reflect internal belief states during perceptual decisions, scaling with decision confidence and prediction errors.