Matthew J. McGinley

Leveraging clinical sleep data across multiple pediatric cohorts for insights into neurodevelopment: the Retrospective Analysis of Sleep in Pediatric (RASP) cohorts study

The paper analyzes sleep data from 1527 pediatric PSGs across five sites to study neurodevelopmental disorders, identifying sleep architecture disruptions in Down Syndrome and developing a sleep stager and brain age prediction model.

Plasticity and Language in the Anesthetized Human Hippocampus

This study shows that the human hippocampus can process oddball tones and language stimuli, including semantic and grammatical features, even under general anesthesia.

Molecular logic for cellular specializations that initiate the auditory parallel processing pathways

The paper identifies molecular logic underlying cellular specializations in the cochlear nuclear complex using single-nucleus RNA sequencing and Patch-seq.

Cortical acetylcholine dynamics are predicted by cholinergic axon activity and behavior state

The paper examines cortical acetylcholine dynamics during behavioral state transitions, finding that axon activity and behavior predict ACh levels.

Vagus nerve stimulation recruits the central cholinergic system to enhance perceptual learning

This study shows that vagus nerve stimulation enhances perceptual learning in mice by activating the central cholinergic system during auditory tasks.

Strategic stabilization of arousal boosts sustained attention

The paper investigates how arousal and task utility interact to influence sustained attention in mice, finding that arousal stabilizes near optimal levels during high task utility.

Combining pupillometry and drift-diffusion models reveals auditory category learning dynamics

This study combines pupillometry and drift-diffusion models to analyze auditory category learning dynamics, showing that delayed trials reveal distinct learning markers and DDM parameters.

Foraging Under Uncertainty Follows the Marginal Value Theorem with Bayesian Updating of Environment Representations

This study shows that mice follow a modified marginal value theorem with Bayesian updating of environment representations when foraging under uncertainty.

Auditory accessory stimulus boosts pupil-linked arousal and reduces choice bias

The paper uses an auditory accessory stimulus to show that increased pupil-linked phasic arousal reduces choice bias without affecting response caution.

Goal-directed motor actions drive acetylcholine dynamics in sensory cortex

This study shows that acetylcholine dynamics in sensory cortex are driven by goal-directed motor actions rather than sensory cues or rewards during task learning.

Graded recruitment of pupil-linked neuromodulation by parametric stimulation of the vagus nerve

This study uses pupil dilation as a biosensor to assess real-time effects of vagus nerve stimulation on brain state in mice.

Phasic arousal suppresses biases in mice and humans across domains of decision-making

This study shows that phasic arousal suppresses decision biases in both mice and humans across different decision-making domains and sensory systems.