Author

Zakir Mridha

Baylor College of MedicineORCID 0000-0002-9772-9812Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:electronic health records· 1 Approach:statistical model· 1

Frequent Co-Authors

Matthew J. McGinleyiD· 4 shared Jan Willem de GeeiD· 3 shared Wenhao ZhangiD· 2 shared Yanchen ShiiD· 2 shared Yulong LiiD· 2 shared Aaron J. SuminskiiD· 1 shared Andrew ErskineiD· 1 shared Brandon MunniD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersNeuroscience

Matthew J. McGinleyORCID

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4 papers

Recent·Most cited

Cortical acetylcholine dynamics are predicted by cholinergic axon activity and behavior state

Erin Neyhart, Na Zhou, Brandon Munn, Robert Law, Cameron L. Smith, Zakir Mridha, Francisco A. Blanco, Guochuan Li, Yulong Li, Ming Hu, Matthew J. McGinley, James M. Shine, Jacob Reimer

The paper examines cortical acetylcholine dynamics during behavioral state transitions, finding that axon activity and behavior predict ACh levels.

Cell Reports · Oct 1, 2024Peer-reviewedNeuroscience

Strategic stabilization of arousal boosts sustained attention

Jan Willem de Gee, Zakir Mridha, Marisa Hudson, Yanchen Shi, Hannah Ramsaywak, Spencer Smith, Nishad Karediya, Matthew Thompson, Kit Jaspe, Hong Jiang, Wenhao Zhang, Matthew J. McGinley

The paper investigates how arousal and task utility interact to influence sustained attention in mice, finding that arousal stabilizes near optimal levels during high task utility.

Current Biology · Aug 15, 2024Peer-reviewedNeuroscience

Goal-directed motor actions drive acetylcholine dynamics in sensory cortex

Jing Zou, Jan Willem de Gee, Zakir Mridha, Simon Trinh, Andrew Erskine, Miao Jing, Jennifer Z. Yao, Stefanie Walker, Yulong Li, Matthew J. McGinley, Samuel Andrew Hires

This study shows that acetylcholine dynamics in sensory cortex are driven by goal-directed motor actions rather than sensory cues or rewards during task learning.

bioRxiv · Dec 21, 2021 · PreprintNeuroscience

Graded recruitment of pupil-linked neuromodulation by parametric stimulation of the vagus nerve

Zakir Mridha, Jan Willem de Gee, Yanchen Shi, Rayan Alkashgari, Justin C. Williams, Aaron J. Suminski, Matthew Peter Ward, Wenhao Zhang, Matthew J. McGinley

This study uses pupil dilation as a biosensor to assess real-time effects of vagus nerve stimulation on brain state in mice.

Nature Communications · Mar 9, 2021Peer-reviewedNeuroscience