Author

Jannik Zimmermann

Saarland UniversityORCID 0000-0002-3336-042XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

Bruce MorganiD· 3 shared Jan RiemeriD· 2 shared Lukas Lang· 2 shared Marcel DeponteiD· 2 shared Adriana Zardini BuzattoiD· 1 shared Ana M. TomásiD· 1 shared Anja TurschiD· 1 shared Armindo SalvadoriD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

Bruce MorganORCID

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Author profile →

3 papers

Recent·Most cited

The ER Thioredoxin-Related Transmembrane Protein TMX2 Controls Redox-Mediated Tethering of ER-Mitochondria Contacts (ERMCS)

Junsheng Chen, Megan C. Yap, Arthur Bassot, Danielle M. Pascual, Tadashi Makio, Jannik Zimmermann, Heather Mast, Rakesh Kumar Bhat, Samuel G. Fleury, Yuxiang Fan, Adriana Zardini Buzatto, Jack Moore, Klaus Ballanyi, Liang Li, Michael Overduin, , Thomas Simmen

This paper identifies TMX2 as a regulator of ER-mitochondria contacts by preventing TOM70 sulfenylation, linking its dysfunction to neurodevelopmental disorders.

Cell Reports · Oct 31, 2025Peer-reviewedCell Biology

Heterooligomerization drives structural plasticity of eukaryotic peroxiredoxins

Jannik Zimmermann, Lukas Lang, Julia Malo Pueyo, Mareike Riedel, Khadija Wahni, Dylan Stobbe, Christopher Lux, Steven Janvier, Didier Vertommen, Svenja Lenhard, Frank Hannemann, Helena Castro, Ana M. Tomás, Johannes M. Herrmann, Armindo Salvador, , Bruce Morgan

The paper shows that eukaryotic Prx1/AhpC-type peroxiredoxins form heterooligomers, which modulate their structure and stability, challenging the previous belief in homooligomerization.

bioRxiv · Mar 3, 2025 · PreprintBiochemistry

Tsa1 is the dominant peroxide scavenger and a source of H2O2-dependent GSSG production in yeast

Jannik Zimmermann, Lukas Lang, Gaetano Calabrese, Hugo Laporte, Prince Saforo Amponsah, Christoph Michalk, Tobias Sukmann, Julian Oestreicher, Anja Tursch, Esra Peker, Theresa N E Owusu, Matthias Weith, Letícia Prates Roma, Marcel Deponte, Jan Riemer, Bruce Morgan

This study identifies Tsa1 as the primary peroxide scavenger in yeast and shows it can generate GSSG under H2O2 conditions.

Free Radical Biology and Medicine · Nov 6, 2024Peer-reviewedBiochemistry