Global-scale CRISPR gene editor specificity profiling by ONE-seq identifies population-specific, variant off-target effects
Karl Petri, Daniel Y. Kim, Kanae E. Sasaki, Matthew C. Canver, Xiao Wang, Hina Shah, Hyunho Lee, Joy E. Horng, Kendell Clement, Sowmya Iyer, Sara P. Garcia, Jimmy A. Guo, Gregory A. Newby, Luca Pinello, David R. Liu, , Vikram Pattanayak
ONE-seq identifies population-specific off-target effects of CRISPR gene editors using global human genome sequence diversity.
bioRxiv · Apr 5, 2021 · PreprintMolecular Biology