Author

Milica A. Margeta

Massachusetts Eye and Ear InfirmaryORCID 0000-0002-5902-4168Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Anthony MukwayaiD· 1 shared Bin YaniD· 1 shared Chiara Romano· 1 shared Daniel Enrique MaidanaiD· 1 shared David A. WeitziD· 1 shared Demetrios G. VavvasiD· 1 shared Eleftherios I. PaschalisiD· 1 shared Emil Kriukov· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Anthony MukwayaORCID

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2 papers

Recent·Most cited

Single-cell transcriptome of retinal myeloid cells in response to transplantation of human neurons reveals reversibility of microglial activation

Emil Kriukov, Anthony Mukwaya, Paul Francis Cullen, George Baldwin, Volha V. Malechka, Nasrin Refaian, Nikita Bagaev, Everett Labrecque, Sthavir Vinjamuri, Milica A. Margeta, Petr Y. Baranov

This study uses single-cell RNA sequencing to analyze retinal myeloid cell activation following human neuron transplantation, revealing reversible activation trajectories similar to disease-associated microglia.

bioRxiv · May 16, 2025 · PreprintNeuroscience

Chromatin and transcriptional adaptation accompany monocyte engraftment in the injured retina

Jie Liu, Fengyang Lei, Chiara Romano, Bin Yan, Tain Cao, Naiwen Cui, Jyoti Sharma, Victor Correa, Lara Roach, Savvas Kikolaou, Kristen M. Pitts, James Chodosh, Daniel Enrique Maidana, Demetrios G. Vavvas, Milica A. Margeta, , Eleftherios I. Paschalis

The paper examines how engrafted monocytes adapt chromatin and transcriptionally in the injured retina, showing shared and distinct features with host microglia.

bioRxiv · Sep 9, 2024 · PreprintImmunology