Heinrich Jasper

The paper designs Müller glia-specific cis-regulatory elements using deep learning and validates their function in vivo.

This study identifies how aging impairs colonic regeneration in mice by promoting a fetal-like epithelial state through sustained IFNγ signaling.

This study shows that oncogenic RasV12 activates Dorsal/NF-κB signaling, promoting tumor growth and malignancy in Drosophila melanogaster tumors.

The paper identifies COPD risk genes using Drosophila melanogaster, validating their role in epithelial barrier function through nAchR signaling in the gut.

The paper presents an aging Drosophila cell atlas, identifies cell type-specific aging patterns, and shows ribosomal gene expression as a conserved aging predictor.

The paper creates a single-cell transcriptomic atlas of the adult fruit fly, identifying over 250 cell types and analyzing gene signatures and sexual dimorphism across tissues.

The paper identifies Klumpfuss as a transcription factor that restricts enteroblast fate to enterocytes in Drosophila via Notch signaling.