Philippe Marin

Physical interaction with Ephrin B1 promotes CXCR4 intracellular localization and oncogenic potential

This study identifies Ephrin B1 as a key mediator of CXCR4 tumorigenic signaling by promoting its intracellular localization and inhibiting surface expression and signaling.

A reciprocal interplay between 5-HT2A and mGlu5 receptors underlies neuroplasticity

This study shows that psychedelics induce neuroplasticity through a reciprocal interaction between 5-HT2A and mGlu5 receptors involving Shank3.

CITE-seq reveals inhibition of NF-kB pathway in B cells from vitamin D-treated multiple sclerosis patients

The paper uses CITE-seq to analyze B cells from vitamin D-treated MS patients, identifying NF-kB pathway inhibition as a potential mechanism for vitamin D's protective effects.

Syndecan-1 as specific cerebrospinal fluid biomarker of multiple sclerosis

The paper identifies Syndecan-1 as a specific cerebrospinal fluid biomarker for multiple sclerosis, improving diagnostic and prognostic accuracy compared to existing markers.

Tau hyperphosphorylation on T217 in cerebrospinal fluid is specifically associated to amyloid-β pathology

The paper shows that hyperphosphorylation of tau at T217 in cerebrospinal fluid is specifically linked to amyloid-β pathology in Alzheimer's disease.