Author

Nell Klimpert

Brown UniversityORCID 0000-0002-6166-8026Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:ChIP-seq· 1

Frequent Co-Authors

Alexander FleischmanniD· 4 shared Andreas T. SchaeferiD· 3 shared David H. BranniD· 2 shared Mihály KöllőiD· 2 shared Anton CrombachiD· 1 shared Ariel Pourmorady· 1 shared Beka Stecky· 1 shared Benjamin Shykind· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersNeuroscience

Alexander FleischmannORCID

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4 papers

Recent·Most cited

A spatial code governs olfactory receptor choice and aligns sensory maps in the nose and brain

David H. Brann, Tatsuya Tsukahara, Cyrus Tau, Dennis Kalloor, Rylin W. Lubash, Lakshanyaa Thamarai Kannan, Nell Klimpert, Mihály Köllő, Martín Escamilla-Del-Arenal, Bogdan Bintu, Andreas T. Schaefer, Alexander Fleischmann, Thomas C. Bozza, Sandeep Robert Datta

The paper shows that olfactory receptor expression in the nose follows a spatial code controlled by a retinoic acid gradient, aligning epithelial and brain maps.

Cell · Apr 29, 2026Peer-reviewedNeuroscience

3D spatial transcriptomics reveals the molecular structure of input and output pathways in the mouse olfactory bulb

Nell Klimpert, Mihály Köllő, David H. Brann, Chichun Tan, David J. Barry, Ying Ma, Andreas T. Schaefer, Alexander Fleischmann

The paper uses 3D spatial transcriptomics to map the molecular organization of the mouse olfactory bulb, revealing symmetric glomeruli and asymmetric deeper layer cells.

bioRxiv · Feb 19, 2025 · PreprintNeuroscience

Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice

Elizaveta Bashkirova, Nell Klimpert, Kevin Monahan, Christine E. Campbell, Jason M. Osinski, Longzhi Tan, Ira Schieren, Ariel Pourmorady, Beka Stecky, Gilad Barnea, Xiaoliang Sunney Xie, Ishmail Abdus-Saboor, Benjamin Shykind, Bianca Jones Marlin, Richard M. Gronostajski, , Stavros Lomvardas

The paper shows that opposing epigenetic forces in olfactory progenitors spatially restrict stochastic OR choice through transcription and silencing influenced by NFIA, B, and X gradients.

eLife · May 12, 2023Peer-reviewedGenomics

Molecular characterization of projection neuron subtypes in the mouse olfactory bulb

Sara Zeppilli, Tobias Ackels, Robin Attey, Nell Klimpert, Kimberly Ritola, Stefan Boeing, Anton Crombach, Andreas T. Schaefer, Alexander Fleischmann

The paper identifies molecular markers and gene regulatory mechanisms for projection neuron subtypes in the mouse olfactory bulb using single nucleus and bulk RNA sequencing.

eLife · Jul 22, 2021Peer-reviewedNeuroscience