Author

Mohamed A. Nasr

PROTEOORCID 0000-0002-8921-6574Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:yeast· 3 Approach:experimental assay· 2 Research Focus:protein design· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

David H. KwaniD· 3 shared Vincent J. J. MartiniD· 3 shared Adrien KnoopsiD· 1 shared Alexei V. SavchenkoiD· 1 shared Chester PhamiD· 1 shared Mackenzie ThornburyiD· 1 shared Meghan Davies· 1 shared P.J. StogiosiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersSynthetic Biology

David H. KwanORCID

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3 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintNov 3, 2026

Biosensor-guided genome-wide CRISPR screens enable cis,cis-muconic acid overproduction in yeast

Mohamed A. Nasr, Adrien Knoops, Mackenzie Thornbury…·Vincent J.J. Martin

This study uses biosensor-guided CRISPR screens in yeast to identify genetic targets that enhance production of cis,cis-muconic acid and protocatechuic acid.

DOI 10.64898/2026.10.31.762157

yeastCRISPR screen

Synthetic BiologyFEBS JournalPeer-reviewedMay 2, 2024

Functional and Structural Characterization of an IclR Family Transcription Factor for the Development of Dicarboxylic Acid Biosensors

Chester Pham, Mohamed A. Nasr, T. Skarina…·Alexei V. Savchenko

This paper characterizes the PcaR transcription factor, solving its crystal structures and demonstrating its function as a dicarboxylic acid biosensor in yeast.

7 citations

yeastprotein structure

Synthetic BiologyNucleic Acids ResearchPeer-reviewedJun 28, 2023

Divergent Directed Evolution of a TetR-type Repressor Towards Aromatic Molecules

Mohamed A. Nasr, Vincent J. J. Martin, David H. Kwan

This paper engineers a TetR-type repressor to recognize multiple aromatic inducers and demonstrates its use in both prokaryotic and eukaryotic systems.

19 citations

E. coliyeast