Author

Justin C. Boucher

Moffitt Cancer CenterORCID 0009-0008-8936-0470Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Ahmad A. TarhiniiD· 1 shared Alyssa ObermayeriD· 1 shared Anna L Austin· 1 shared Awino Maureiq E. Ojwang’iD· 1 shared Constanza Savid-FronteraiD· 1 shared Cooper J. SaileriD· 1 shared Dongliang DuiD· 1 shared Eduardo Cortes GomeziD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Ahmad A. TarhiniORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 6, 2025

The Th1/Th17 axis regulates chimeric antigen receptor (CAR) T cell therapy toxicities

Payal Goala, Yongliang Zhang, Nolan Beatty…·Marco L. Davila

This study identifies a Th1/Th17 imbalance driven by IFN{gamma} that causes cytokine release syndrome and neutropenia in CAR-T therapy, suggesting IFN{gamma} blockade as a potential treatment.

1 citation

mousehuman

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ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewedFeb 1, 2025

Effector T Cells under Hypoxia have an Altered Transcriptome Similar to Tumor-Stressed T Cells Found in Non-Responsive Melanoma Patients

Mate Z Nagy, Lourdes Plaza-Rojas, Justin C. Boucher…·Jose Alejandro Guevara-Patino

This study shows hypoxia alters T cell transcriptomes in melanoma, correlating with poor clinical outcomes in non-responders to immunotherapy.

13 citationstop 3%

humanbulk RNA-seq

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