J.S. Gregory

Dissecting the genetic architecture of knee alignment reveals its contribution to osteoarthritis risk

This study identifies 20 genetic loci associated with knee alignment and shows genetic correlation with knee osteoarthritis, suggesting osteoarthritis may causally influence alignment.

Hip joint space width is causally related to hip osteoarthritis risk via distinct protective and susceptibility mechanisms: findings from a genome-wide association study meta-analysis

This study identifies genetic determinants of hip joint space width and finds they have opposing causal effects on hip osteoarthritis risk through distinct mechanisms.

Genome-wide associations reveal human-mouse genetic convergence and modifiers of myogenesis, CPNE1 and STC2

This study identifies genetic loci associated with muscle mass in humans and mice, finds shared genetic mechanisms, and identifies CPNE1 and STC2 as modifiers of myogenesis.

Genome wide association analysis in a mouse advanced intercross line

The paper uses a mouse advanced intercross line to identify genetic associations and eQTLs for traits related to human health and disease.