Author

Florence T.H. Wu

University Health NetworkORCID 0000-0002-6439-4606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian Gerold SacheriD· 1 shared Alexander Wang YingiD· 1 shared Caitlyn Weston· 1 shared Cigall KadochiD· 1 shared Claudia Gentile· 1 shared Daren C. CardiD· 1 shared Francesco FacchinettiiD· 1 shared Jens KöhleriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Adrian Gerold SacherORCID

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1 paper

Recent·Most cited

mSWI/SNF complex inhibition sensitizes KRAS-mutant lung cancers to targeted therapies via epithelial-mesenchymal subversion

Claudia Gentile, William W. Feng, Sean M. Lenahan, Alexander Wang Ying, Daren C. Card, Florence T.H. Wu, Nhu‐An Pham, Nikolina Radulovich, Pinjiang Mary Cao, K. Hueniken, Quan Li, Ming‐Sound Tsao, JOSEPH S. KULESZA, Madeline M. Hinkley, Lishu Liao, , Cigall Kadoch

This study shows that inhibiting mSWI/SNF complexes enhances the effectiveness of KRAS inhibitors in lung cancers by reversing epithelial-mesenchymal transition resistance.

bioRxiv · Mar 1, 2026 · PreprintCancer Biology