Nikolina Radulovich

Tumor Microenvironment Modulates Lineage Plasticity in Lung Squamous Cell Carcinoma

This study shows that the tumor microenvironment influences lineage plasticity in lung squamous cell carcinoma by modulating HIF1 and SOX2 pathways and ECM remodeling.

mSWI/SNF complex inhibition sensitizes KRAS-mutant lung cancers to targeted therapies via epithelial-mesenchymal subversion

This study shows that inhibiting mSWI/SNF complexes enhances the effectiveness of KRAS inhibitors in lung cancers by reversing epithelial-mesenchymal transition resistance.

MRCKα represses GEF-H1 mediated RhoA activation to promote ovarian cancer spheroid growth and invasion.

This study identifies MRCKα as a repressor of GEF-H1-mediated RhoA activation, promoting ovarian cancer spheroid growth and invasion.

Whole Genomes Define Concordance of Matched Primary, Xenograft, and Organoid Models of Pancreas Cancer

The paper compares whole-genome data from primary pancreatic cancer, xenografts, and organoids to assess genetic concordance across different models.