The paper conducts a genetic analysis of immune biomarkers across pregnancy timepoints, identifying heritable and genome-wide significant associations and highlighting timepoint-specific and pregnancy-unique findings.

medRxiv · Jan 2, 2026 · PreprintGenetic & Genomic Medicine

DISC1-PML protein interaction for congenital CMV infection-induced cortical neural progenitor deficit: perturbance of host signaling via viral IE1

Atsushi Saito, Stephanie K. Tankou, Kazuhiro Ishii, Makiko Sakao‐Suzuki, Edwin C. T. Oh, Hannah Murdoch, Ho Namkung, Sunday Adelakun, Keiko Furukori, Masahiro Fujimuro, Paolo Salomoni, Gerd G. Maul, Gary S. Hayward, Qiyi Tang, Robert H. Yolken, , Akira Sawa

This study identifies the role of CMV viral protein IE1 in disrupting host DISC1-PML interaction, leading to neural progenitor deficits in congenital CMV infection.

bioRxiv · Sep 3, 2025 · PreprintDevelopmental Biology

Maternal antibodies to gliadin and autism spectrum disorders in offspring - A population-based case-control study in Sweden

Renee M. Gardner, Ida Samuelsson, Emily G. Severance, Hugo Sjöqvist, Robert H. Yolken, Christina Dalman, Håkan Karlsson

This study examines if high maternal levels of anti-gliadin antibodies during pregnancy and birth are linked to reduced odds of autism spectrum disorder with intellectual disability in offspring.

Autism Research · Jul 2, 2021Peer-reviewedMolecular Biology

Exome sequencing in bipolar disorder reveals shared risk gene AKAP11 with schizophrenia

Duncan S. Palmer, Daniel P. Howrigan, Sinéad B. Chapman, Rolf Adolfsson, Nicholas James Bass, Douglas Blackwood, Marco P. Boks, Chia‐Yen Chen, Claire L. Churchhouse, Aiden Peter Corvin, Nick J. Craddock, David Curtis, Arianna Di Florio, Faith Dickerson, Fernando S. Goes, , Benjamin M. Neale

The paper reports exome sequencing findings in bipolar disorder, identifying AKAP11 as a shared risk gene with schizophrenia through ultra-rare protein-truncating variants.

medRxiv · Mar 9, 2021 · PreprintGenetic & Genomic Medicine