Yi‐Chih Lin

This study visualizes G2L4 reverse transcriptase's role in DNA repair via microhomology-mediated end joining using high-speed atomic force microscopy.

The paper develops fluorescent membrane scaffold proteins for nanodiscs, enabling applications like monitoring membrane protein interactions through fluorescence resonance energy transfer.

This paper develops a covalent PFKL activator that disrupts cancer cell metabolism and delivers a cytotoxic payload, showing efficacy in vitro and in vivo.

This study uses HS-AFM and simulations to show ligand-dependent assembly switching of human PFKL, revealing structural changes in response to ATP and F6P.