Author

Leah S. Hohman

University of British ColumbiaORCID 0000-0002-6520-1060Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alexandros PolyzoisiD· 1 shared Annie PuiD· 1 shared Ben Perks· 1 shared Bruna Araújo DavidiD· 1 shared Camila Gaio· 1 shared Chris TiesseniD· 1 shared David S Guttman· 1 shared Donny Chan· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Alexandros PolyzoisORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 19, 2026

Pre-existing Th1 immunity is abrogated by ongoing recruitment of monocytic host cells that are refractory to activation

Matheus Batista Heitor Carneiro, Santiago Aguiar Espellet Soares, Chris Tiessen…·Nathan C. Peters

The paper shows that pre-existing Th1 immunity is overcome by monocyte-derived macrophages that create a pathogen niche, and that checkpoint blockade or depletion of these cells improves parasite control.

DOI 10.64898/2026.08.14.744955

mouseCITE-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 27, 2024

Mining for disease-associated microbial metabolites in an age-dependent model of multiple sclerosis

Annie Pu, Naomi M. Fettig, Alexandros Polyzois…·Lisa C. Osborne

The paper identifies a microbial metabolite, indole 3-propionic acid, that can reverse non-remitting EAE in aged mice, suggesting therapeutic potential for progressive MS.

3 citations

mousemetabolomics

𝕏 PostBluesky