Author

Carlo Giannangelo

Monash UniversityORCID 0000-0002-6654-7266Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:plant (other)· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Darren J. CreekiD· 2 shared Ghizal SiddiquiiD· 2 shared Amanda De PaoliiD· 1 shared Annie Roys· 1 shared Bethany M. AndersoniD· 1 shared Christopher A. MacRaildiD· 1 shared Haijian ZhangiD· 1 shared Joshua P. MorrowiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

Darren J. CreekORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyInternational Journal for Parasitology Drugs and Drug ResistancePeer-reviewedNov 24, 2025

Validation of Solvent Proteome Profiling for Antimalarial Drug Target Deconvolution

Yijia Ji, Joshua P. Morrow, Christopher A. MacRaild…·Ghizal Siddiqui

This study validates solvent proteome profiling (SPP) as a method to identify antimalarial drug targets in Plasmodium falciparum by detecting ligand-induced protein stability changes.

2 citations

plant (other)proteomics

𝕏 PostBluesky

MicrobiologybioRxivPreprintOct 5, 2025

PfK13-associated artemisinin resistance slows drug activation and enhances antioxidant defence, which can be overcome with sulforaphane.

Ghizal Siddiqui, Carlo Giannangelo, Natalie A. Counihan…·Darren J. Creek

This study identifies PfK13 mutations as drivers of artemisinin resistance by enhancing antioxidant defenses, which can be counteracted by sulforaphane.

DOI 10.1101/2025.10.05.680568

plant (other)proteomics

𝕏 PostBluesky