Pinky Kain

Enabling subcellular DESI-MSI for broad adoption: Acquisition, analysis, and application

This paper demonstrates subcellular mass spectrometry imaging using standard hardware and open-source software, enabling accessible spatial metabolomics with subcellular resolution.

Peripheral metabolic dysfunction drives sleep disruption in TDP-43 proteinopathy

This study shows that peripheral metabolic dysfunction, not just neuronal loss, causes sleep disruption in TDP-43 proteinopathy by identifying SIK3 as a key regulator.

MSI.EAGLE: An Open-Source GUI for Streamlined Mass Spectrometry Imaging Analysis

MSI.EAGLE provides an open-source GUI for MSI analysis, integrating advanced tools to simplify data processing and visualization for non-specialists.

Altered Metabolism During the Dark Period in Drosophila Short Sleep Mutants

This study examines metabolic changes in Drosophila short sleep mutants during the dark period, revealing altered metabolite levels and rhythmicity patterns compared to wild type.

Glucose Challenge Uncovers Temporal Fungibility of Metabolic Homeostasis over a day:night cycle

This study uses isotope tracing to show rhythmic glucose metabolism in Drosophila, revealing internal mechanisms controlling metabolic homeostasis across day and night.

Activity and state-dependent modulation of salt taste behavior via pharyngeal neurons in Drosophila melanogaster

This study investigates how Drosophila modulates high salt intake based on diet and state, showing that pharyngeal LSO neurons and dopamine regulate this behavior.