Richard Glenn Kibbey

This study shows that beta cells drive pancreatic ductal adenocarcinoma development through endocrine-exocrine signaling, with obesity enhancing this process via CCK+ beta cell adaptation.

The paper investigates tissue-specific metabolic functions of GPI-1 in C. elegans, showing isoform-specific localization and metabolic roles in different tissues.

This study identifies metabolic pathways associated with stress hyperglycemia during cardiac surgery using longitudinal metabolomics and machine learning.

This paper shows that renalase activates mitochondrial leak metabolism to enhance protein synthesis and protect cells from stress and injury.

This study uses isotope tracing to show rhythmic glucose metabolism in Drosophila, revealing internal mechanisms controlling metabolic homeostasis across day and night.

Corna is a Python tool for natural abundance correction in isotope tracer experiments, offering integrated workflows and reducing processing times.

The paper evaluates how sampling time points affect the sensitivity and variability of metabolic flux estimates in isotopic labeling experiments and suggests strategies to optimize experimental design.