Todd D. Schell

This study shows PD-1 in CD4+ T cells balances antiviral defense and neuroinflammation during polyomavirus CNS infection by modulating CD8+ T cell responses.

This study shows that IGF2BP family proteins suppress RNA-sensing pathways by binding TNFAIP3 mRNA, reducing innate immune signaling in AML cells.

This study identifies GDF-15 as a mechanosensing-regulated driver of melanoma pathogenesis, linking mechanical stress, vascular disorganization, and immune suppression.

This study identifies the BNIP3-mTOR signaling axis as a mediator of resistance to MET inhibition in glioblastoma and shows that combined MET and mTOR inhibition synergistically enhances anti-tumor effects.