Author

Arati Sharma

Penn State Milton S. Hershey Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Ahsan PolashiD· 1 shared Alex Hastie· 1 shared Alexis MorrisseyiD· 1 shared Barbara Miller· 1 shared Charyguly AnnageldiyeviD· 1 shared Cheryl A. KelleriD· 1 shared Christopher PooliD· 1 shared Darrin Bann· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Ahsan PolashORCID

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Author profile →

2 papers

Recent·Most cited

Oncofetal RNA-binding proteins of IGF2BP family suppress IRF-3 and NF-kB dependent transcription downstream of cytosolic RNA sensors

Garrett Knox, Ruba Agili-Shaban, Alexis Morrissey, Karamveer Karamveer, Ahsan Polash, Maria Wohlbowne, Stefanija Kinzy, Cheryl A. Keller, Todd D. Schell, Jeremy A. Hengst, George‐Lucian Moldovan, Junjia Zhu, Arati Sharma, Hong Zheng, Edward Harhaj, , Irina A. Elcheva

This study shows that IGF2BP family proteins suppress RNA-sensing pathways by binding TNFAIP3 mRNA, reducing innate immune signaling in AML cells.

bioRxiv · Jul 29, 2026 · PreprintCancer Biology

An Integrated Framework for Genome Analysis Reveals Numerous Previously Unrecognizable Structural Variants in Leukemia Patients' Samples

Jie Xu, Fan Song, Emily Schleicher, Christopher Pool, Darrin Bann, Max Hennessy, Kathryn Sheldon, Emma Batchelder, Charyguly Annageldiyev, Arati Sharma, Yuanyuan Chang, Alex Hastie, Barbara Miller, David Goldenberg, Shin Mineishi, , James R. Broach

The paper identifies numerous previously undetected structural variants in leukemia samples using integrated genome analysis and computational methods, revealing their impact on gene expression and patient survival.

bioRxiv · Feb 28, 2019 · PreprintGenomics