Single-cell Genome-and-Transcriptome sequencing without upfront whole-genome amplification reveals cell state plasticity of melanoma subclones
Koen Theunis, Sebastiaan Vanuytven, Irene Claes, Jarne Geurts, Florian Rambow, Daniel V. Brown, Michiel Van der Haegen, Oskar Marín-Béjar, Aljosja Rogiers, Nina Van Raemdonck, Eleonora Leucci, Jonas Demeulemeester, Alejandro Sifrim, Jean‐Christophe Marine, Thierry Voet
This paper introduces Gtag&T-seq, a low-cost single-cell multi-omics method that reveals cell state plasticity and treatment response in melanoma subclones.
Nucleic Acids Research · Feb 21, 2025Peer-reviewedGenomics