Author

Natalie De Geest

Leuven Stem Cell Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3 Neuroscience· 1

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Adrian JaniszewskiiD· 2 shared Annelies Claeys· 2 shared Irene TalóniD· 2 shared Jiekun Yan· 2 shared Juan SongiD· 2 shared Lotte VanheeriD· 2 shared Vincent PasqueiD· 2 shared Bassem A. HassaniD· 1 shared

Activity by Year

2015-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersDevelopmental Biology

Adrian JaniszewskiORCID

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4 papers

Recent·Most cited

Dynamic Erasure of Random X-Chromosome Inactivation during iPSC Reprogramming

Adrian Janiszewski, Irene Talón, Joel Chappell, Samuel Collombet, Juan Song, Natalie De Geest, San Kit To, Greet Bervoets, Oskar Marín-Béjar, Caterina Provenzano, Lotte Vanheer, Jean‐Christophe Marine, Florian Rambow, Vincent Pasque

This study investigates the dynamics of X-chromosome reactivation during mouse iPSC reprogramming, revealing hierarchical gene activation patterns and the role of chromatin regulators.

bioRxiv · Feb 9, 2019Developmental Biology

X Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem Cells Independently of Global DNA Methylation Levels

Juan Song, Adrian Janiszewski, Natalie De Geest, Lotte Vanheer, Irene Talón, Mouna El Bakkali, Taeho Oh, Vincent Pasque

This study shows that X-chromosome dosage in mouse iPSCs affects chromatin accessibility, transcriptome, growth, and pluripotency exit, largely independent of DNA methylation.

Stem Cell Reports · Jan 10, 2019Peer-reviewedDevelopmental Biology

Post-transcriptional modulation of Dscam1 enhances axonal growth in development and after injury

Marta Koch, Maya Nicolas, Marlen Zschaetzsch, Natalie De Geest, Annelies Claeys, Jiekun Yan, Matthew Morgan, Maria‐Luise Erfurth, Matthew G. Holt, Dietmar Schmucker, Bassem A. Hassan

This study identifies a conserved signaling pathway involving Dscam1, Faf/Usp9x, and JNK that promotes axonal growth in Drosophila and mammals after CNS injury.

Frontiers in Cellular Neuroscience · Feb 7, 2018Peer-reviewedNeuroscience

The Drosophila Neurogenin, Tap, controls axonal growth through the Wnt adaptor protein Dishevelled

Liqun Yuan, Shu Hu, Zeynep Okray, Xi Ren, Natalie De Geest, Annelies Claeys, Jiekun Yan, Eric Bellefroid, Bassem Hassan, Xiao-Jiang Quan

This study shows that Tap, the Drosophila Neurogenin homologue, regulates axonal growth by controlling Dishevelled levels in the Wnt pathway.

bioRxiv · Dec 15, 2015Developmental Biology