Florence Fauvelle

Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy

This study shows that daily intermittent fasting reduces seizure frequency and improves sociability in mouse models of absence epilepsy without adverse effects.

The metabolic kinase LKB1 shapes the enteric nervous system bymitigating the oxidative stress and p53 activity

This paper shows that LKB1 is essential for ENS development by reducing oxidative stress and p53 activity, leading to hypoganglionosis and digestive issues when LKB1 is lost.

Re-routing metabolism by the mitochondrial pyruvate carrier inhibitor MSDC-0160 attenuates neurodegeneration in a rat model of Parkinson's disease

This study shows that MSDC-0160, a mitochondrial pyruvate carrier inhibitor, reduces neurodegeneration in a rat Parkinson's disease model by altering energy metabolism and neuroinflammation.