Author

Marcus Y. Chin

Denali Therapeutics (United States)ORCID 0000-0002-7037-1603Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ana María CuervoiD· 1 shared Anil RanaiD· 1 shared Bangyan Liu· 1 shared Bruce L. MilleriD· 1 shared Carlo CondelloiD· 1 shared Chao WangiD· 1 shared David A. JoyiD· 1 shared David LeiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Ana María CuervoORCID

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2 papers

Recent·Most cited

Cell BiologySLAS DISCOVERYPeer-reviewedJan 6, 2025

Novel high-content and open-source image analysis tools for profiling mitochondrial morphology in neurological cell models

Marcus Y. Chin, David A. Joy, Madhuja Samaddar…·Meredith Calvert

The paper introduces MitoProfilerHC and an open-source version of MitoProfiler to quantify mitochondrial morphology in cells using high-content analysis and napari.

7 citations

humanmouse

𝕏 PostBluesky

NeuroscienceNature CommunicationsPeer-reviewedApr 12, 2022

Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy

Chao Wang, Li Fan, Rabia R. Khawaja…·Li Gan

This study shows that microglial NF-κB signaling drives tau spreading and toxicity in a mouse model of tauopathy, with inhibition reducing tau pathology and cognitive deficits.

333 citationstop 1%

mousebulk RNA-seq

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