Bangyan Liu

TRAPPC8 Is an Endogenous Brake on UFMylation That Suppresses Tauopathy

This study identifies TRAPPC8 as a brake on UFMylation that suppresses tauopathy by interacting with UBA5, showing its therapeutic potential in Alzheimer's disease.

Soluble DLK1 secreted by telomere-shortening-induced senescent microglia impairs oligodendrocyte functions and alters neuronal activity

This study identifies soluble DLK1 from senescent microglia as a factor impairing oligodendrocyte function and altering neuronal activity in aging.

DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity

This study shows that DAP12 deficiency reduces tau-induced inflammation and myelin loss in mice, despite increased tau pathology, by altering microglia-oligodendrocyte interactions.

Machine learning approaches based on fibroblast morphometry confidently identify stress but have limited ability to predict ALS

The paper uses machine learning on fibroblast morphometry to predict stress but finds limited ability to distinguish ALS from controls.

Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy

This study shows that microglial NF-κB signaling drives tau spreading and toxicity in a mouse model of tauopathy, with inhibition reducing tau pathology and cognitive deficits.