Author

Andrew P. Kurland

Icahn School of Medicine at Mount SinaiORCID 0000-0002-4982-4081Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Adam R. WardiD· 1 shared Adolfo García‐SastreiD· 1 shared Alberto BosqueiD· 1 shared Ali DaneshiD· 1 shared Andrea GramaticaiD· 1 shared Ann Anu KurianiD· 1 shared Ashley RichardsoniD· 1 shared Brad R. RosenbergiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Adam R. WardORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Broad-spectrum RNA antiviral inspired by ISG15-/- deficiency

Yemsratch T. Akalu, Roosheel S. Patel, Justin D. Taft, Rodrigo Cañas‐Arranz, Ashley Richardson, Sofija Buta, Marta Martín-Fernández, Rebecca L. Pearl, Gayatri Mainkar, Andrew P. Kurland, Haylen Rosberger, Diana D. Kang, Ann Anu Kurian, Keerat Kaur, Jennie B. Altman, , Dusan Bogunovic

The paper identifies a set of 10 ISGs that confer broad-spectrum antiviral resistance and demonstrates their efficacy in protecting against multiple viruses in vivo.

Science Translational Medicine · Aug 13, 2025Peer-reviewedImmunology

The EZH2 inhibitor tazemetostat mitigates HIV immune evasion, reduces reservoir formation, and promotes durable CD8+ T-cell revitalization

Andrea Gramatica, Itzayana G. Miller, Adam R. Ward, Khan Farzana, Tyler J. Kemmer, Jared Weiler, Tan Thinh Huynh, Paul Zumbo, Andrew P. Kurland, Louise Leyre, Yanqin Ren, Thaís Klevorn, Dennis C. Copertino, Uchenna K. Chukwukere, Callie Levinger, , R. Brad Jones

The paper shows that tazemetostat reduces HIV reservoirs and improves CD8+ T-cell function by increasing MHC-I expression and promoting anti-HIV immune responses.

Cell Reports · May 1, 2025Peer-reviewedImmunology