Author

Robert F. Hennigan

Cincinnati Children's Hospital Medical CenterORCID 0000-0002-7054-8384Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Nancy RatneriD· 2 shared Jennifer Patritti CramiD· 1 shared Jianqiang WuiD· 1 shared Jose A. Cancelas· 1 shared K. John McLaughlin· 1 shared Katherine E. Chaney· 1 shared Ramya Ravindran· 1 shared Robert A. Coover· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Nancy RatnerORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 13, 2025

Active Merlin Binds RalB to Regulate Exocytosis

Robert F. Hennigan, K. John McLaughlin, Nancy Ratner

This study identifies RalB as a novel binding partner for active Merlin and shows its role in regulating exocytosis through the RalA/B pathway, suggesting therapeutic potential for NF2-related schwannoma.

DOI 10.1101/2025.06.13.659557

humanproteomics

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NeuroscienceeLifePeer-reviewedMar 21, 2022

Purinergic receptor P2RY14 cAMP signaling regulates EGFR-driven Schwann cell precursor self-renewal and nerve tumor initiation in neurofibromatosis.

Jennifer Patritti Cram, Jianqiang Wu, Shinji Kuninaka…·Nancy Ratner

This study identifies P2RY14 as a regulator of cAMP signaling in Schwann cell precursors, showing its role in self-renewal and neurofibroma initiation in NF1 mutant cells.

19 citations

mousestatistical model

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