Meredith K. Mahnke

Similar destabilization of neural dynamics under different general anesthetics

The paper shows that different anesthetics destabilize neural dynamics similarly, affecting recovery and low-frequency power, and linking this to unconsciousness.

State-space trajectories and traveling waves following distraction

The paper shows that after distractions, neural activity in the prefrontal cortex returns to pre-disruption patterns through state-space rotations and traveling waves.

Convergent effects of different anesthetics on changes in phase alignment of cortical oscillations

This study shows that ketamine and dexmedetomidine induce similar cortical phase alignment patterns in nonhuman primates, suggesting a common mechanism for loss of responsiveness.

Evidence for an active handoff between cerebral hemispheres during target tracking

The paper investigates how cerebral hemispheres coordinate during target tracking, finding that alpha and theta power changes signal an active handoff of attention between hemispheres.

Propofol-mediated loss of consciousness disrupts predictive routing and local field phase modulation of neural activity

This study investigates how propofol-induced loss of consciousness affects neural oscillations and spiking activity in monkeys during auditory processing, finding disrupted alpha/beta inhibition and enhanced gamma/spiking.

Propofol anesthesia destabilizes neural dynamics across cortex

This study uses DeLASE to show that propofol anesthesia reduces dynamic stability in macaque cortex, mirroring destabilized linear systems.

Multifunctional fibers enable modulation of cortical and deep brain activity during cognitive behavior in macaques

The paper demonstrates the use of multifunctional fibers to record and modulate neural activity in macaques during cognitive tasks, showing changes in neural activity with local inhibition.

Propofol anesthesia alters cortical traveling waves

This study examines how propofol anesthesia affects cortical traveling waves in non-human primates, finding increased slow-delta waves and decreased higher-frequency waves during loss of consciousness.

Neural effects of propofol-induced unconsciousness and its reversal using thalamic stimulation

This study investigates how propofol induces unconsciousness in non-human primates and how thalamic stimulation reverses its effects by altering neural activity patterns.

Interhemispheric transfer of working memories

The paper shows that visual working memory is transferred between hemispheres through neural activity changes and increased synchrony during a saccade.

Neural signatures of loss of consciousness and its recovery by thalamic stimulation.

This study identifies neural signatures of unconsciousness and shows that thalamic stimulation can reverse these features in anesthetized non-human primates.