Jacob Donoghue

This study uses control-theoretic methods to show that propofol anesthesia reduces interareal control in the brain, leading to a directional breakdown of cortical control.

This paper introduces a Bayesian state-space model to jointly infer oscillatory dynamics and spike-field coupling, showing improved frequency-specific estimates compared to classical methods.

The paper shows that different anesthetics destabilize neural dynamics similarly, affecting recovery and low-frequency power, and linking this to unconsciousness.

The paper shows that after distractions, neural activity in the prefrontal cortex returns to pre-disruption patterns through state-space rotations and traveling waves.

This study investigates how propofol-induced loss of consciousness affects neural oscillations and spiking activity in monkeys during auditory processing, finding disrupted alpha/beta inhibition and enhanced gamma/spiking.

This study uses DeLASE to show that propofol anesthesia reduces dynamic stability in macaque cortex, mirroring destabilized linear systems.

This study shows propofol disrupts sensory signal progression through the cortical hierarchy by affecting both Up and Down states, with persistent responses only in auditory cortex.

This study examines how propofol anesthesia affects cortical traveling waves in non-human primates, finding increased slow-delta waves and decreased higher-frequency waves during loss of consciousness.

This study investigates how propofol induces unconsciousness in non-human primates and how thalamic stimulation reverses its effects by altering neural activity patterns.

The paper shows that visual working memory is transferred between hemispheres through neural activity changes and increased synchrony during a saccade.

This study identifies neural signatures of unconsciousness and shows that thalamic stimulation can reverse these features in anesthetized non-human primates.