Vincent Pascoli

This study shows that repeated optogenetic activation of dopamine neurons induces locomotor sensitization and cross-sensitization to cocaine, demonstrating dopamine's role in behavioral plasticity.

The paper identifies increased AMPA/NMDA ratio at OFC-DS synapses and SPN activity peaks as drivers of compulsive reward seeking in mice.

This paper shows that d-amphetamine and methylphenidate increase GluA1 phosphorylation at Ser845 in mouse cerebellar Bergmann Glia Cells via norepinephrine signaling.

This study shows heroin activates specific dopamine neurons in the ventral tegmental area projecting to the medial shell of the nucleus accumbens, and manipulations of these neurons affect heroin reinforcement.