Jinhu Xiong

TENGU improves spatial transcriptomics by using transcript-signal density for cell segmentation and simulation, enhancing accuracy in complex tissues.

This study shows that increasing autophagy in osteoblast lineage cells via CRISPR activation of Tfeb improves bone mass and strength in mice.

This study creates a harmonized atlas of murine bone-associated cells using single-cell RNA sequencing to clarify cell type designations and identify osteoblast progenitors.