Intawat Nookaew

This paper develops an alignment-free method to design a broad-spectrum RT-qPCR assay for detecting multiple Orthoflavivirus species, achieving high sensitivity and specificity in clinical samples.

TENGU improves spatial transcriptomics by using transcript-signal density for cell segmentation and simulation, enhancing accuracy in complex tissues.

This paper improves eccDNA enrichment and amplification methods, achieving >50% overlap in technical replicates compared to <1% previously observed.

This study investigates how mitochondrial reactive oxygen species (mtROS) affect bone mesenchymal cells, showing impaired mitochondrial function and NAD+ levels, and suggests combined therapies targeting mtROS, senescence, and NAD+ may delay age-related osteoporosis.

This study shows that increasing autophagy in osteoblast lineage cells via CRISPR activation of Tfeb improves bone mass and strength in mice.

CAIM improves microbial taxonomic profiling by using genome coverage instead of relative abundance, showing better performance in identifying species and predicting disease in cancer datasets.

This study creates a harmonized atlas of murine bone-associated cells using single-cell RNA sequencing to clarify cell type designations and identify osteoblast progenitors.

This paper introduces CReSIL 2.0, a software suite for identifying and characterizing extrachromosomal circular DNA from long-read sequences, achieving high accuracy in simulated data.

This paper presents a chromosome-level genome assembly for the black tiger shrimp, enabling the identification of novel growth-associated genes through transcriptome comparison.

Memote, open-source Python software, runs a community-maintained, partly scored test suite (consistency, biomass, annotations, optional experimental data) on SBML-encoded genome-scale metabolic models, once or through continuous integration.

This paper demonstrates a method using long-read nanopore sequencing to directly sequence native RNA viruses, achieving high accuracy and enabling real-time detection of complex viral transcriptomes.

The paper develops ELIGOS, a bioinformatic tool to detect RNA modifications and secondary structures using native RNA sequencing data from E. coli, yeast, and human cells.

The paper creates a database of bacterial genome quality scores to help users filter high-quality genomes for bioinformatics analysis.