Visanu Wanchai

TENGU improves spatial transcriptomics by using transcript-signal density for cell segmentation and simulation, enhancing accuracy in complex tissues.

This paper improves eccDNA enrichment and amplification methods, achieving >50% overlap in technical replicates compared to <1% previously observed.

This study shows that increasing autophagy in osteoblast lineage cells via CRISPR activation of Tfeb improves bone mass and strength in mice.

This study creates a harmonized atlas of murine bone-associated cells using single-cell RNA sequencing to clarify cell type designations and identify osteoblast progenitors.

This paper introduces CReSIL 2.0, a software suite for identifying and characterizing extrachromosomal circular DNA from long-read sequences, achieving high accuracy in simulated data.

This study analyzes over 100,000 E. coli genomes to identify 14 phylogroups, revealing population structure and genomic adaptations in virulence and antibiotic resistance.

The paper develops ELIGOS, a bioinformatic tool to detect RNA modifications and secondary structures using native RNA sequencing data from E. coli, yeast, and human cells.

The paper creates a database of bacterial genome quality scores to help users filter high-quality genomes for bioinformatics analysis.