Author

Sophia R. Meyer

University of MichiganORCID 0000-0002-7301-8370Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Jonathan Z. SextoniD· 2 shared Andrew M. TidballiD· 1 shared Andrew Tucker· 1 shared Angeline WuiD· 1 shared Ashley J. CuttittaiD· 1 shared Benjamin S. HalliganiD· 1 shared Bhargavasai Gunuguntla· 1 shared Charles J. ZhangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

Jonathan Z. SextonORCID

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2 papers

Recent·Most cited

High-Throughput Morphological Profiling of Patient-Derived Human Liver Organoids for Hepatotoxicity Hazard Identification and Compound Prioritization

Sophia R. Meyer, Max A. Garcia, Neil Zhao, Samantha F. Boisvert, Matthew McConnachie, Charles J. Zhang, Benjamin S. Halligan, Andrew M. Tidball, Andrew Tucker, Josepha Kaganove, Jesse W. Wotring, Joel A. Yates, Diana Flores, Robert J. Fontana, Jonathan Z. Sexton

This paper uses patient-derived liver organoids and machine learning to identify hepatotoxic compounds by analyzing morphological changes, achieving high accuracy in distinguishing toxicants from non-toxicants.

bioRxiv · Oct 4, 2026 · PreprintPharmacology & Toxicology

A scalable long-term in vitro model of human colonic epithelium with continuous barrier function

Ashley J. Cuttitta, Sophia R. Meyer, Tristan Frum, Bhargavasai Gunuguntla, Angeline Wu, Sha Huang, Jack Morgan, Michael K. Dame, Jonathan Z. Sexton, Jason R. Spence

This paper develops a long-term in vitro model of human colonic epithelium that maintains barrier function for up to 30 days and responds to various challenges.

bioRxiv · Sep 24, 2025 · PreprintCell Biology