Author

Tia A. Tate

ORCID 0000-0002-7359-1660Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Aarav MehtaiD· 1 shared Alison M. Rojas· 1 shared Caroline A Tomblin· 1 shared Charles GawadiD· 1 shared Christina Ford· 1 shared Dalia FleifeliD· 1 shared Durga M. Arvapalli· 1 shared E. Shelley HwangiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Aarav MehtaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Extrachromosomal DNA Gives Cancer a New Evolutionary Pathway

Yue Wang, Oliver Cope, Jingting Chen, Aarav Mehta, Dalia Fleifel, Christina Ford, Poorya Behnamie, Molly Murray, Santiago Haase, Saygin Gulec, Logan Slade, Tim C. Elston, Philip M. Spanheimer, Caroline A Tomblin, Alison M. Rojas, , Elizabeth Brunk

The paper shows that ecDNA allows tumors to adapt rapidly by maintaining a spectrum of gene expression levels across cells, rather than relying on clonal expansion.

bioRxiv · Apr 26, 2025 · PreprintGenomics

Unifying comprehensive genomics and transcriptomics in individual cells to illuminate oncogenic and drug resistance mechanisms

Jeffrey R. Marks, Jon S. Zawistowski, Isai Salas-González, Tia A. Tate, Tatiana V. Morozova, Jeff G. Blackinton, Durga M. Arvapalli, Swetha Devi Velivela, G. Harton, Charles Gawad, Victor Weigman, E. Shelley Hwang, Jay A. A. West

This study uses ResolveOME to analyze genomic and transcriptomic data in individual cells, revealing mutations and gene expression changes linked to drug resistance and oncogenic mechanisms.

bioRxiv · Apr 29, 2022 · PreprintGenomics