Author

Vikramjeet Singh

Essen University HospitalORCID 0000-0002-7361-8317Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Dirk Matthias HermanniD· 3 shared Matthias GunzeriD· 3 shared Nina HagemanniD· 3 shared Ali Ata TuziD· 2 shared Ayan Mohamud YusufiD· 2 shared Daniel Robert EngeliD· 2 shared Devon SiemesiD· 2 shared Alessio Vittorio ColomboiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersNeuroscience

Dirk Matthias HermannORCID

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Author profile →

4 papers

Recent·Most cited

Histone neutralization protects the ischemic brain against stroke-associated pneumonia

Dongpei Yin, Anran Li, Olga Shevchuk, Ayan Mohamud Yusuf, Janine Gronewold, Stephanie Thiebes, Tobias Tertel, Chen Wang, Nina Hagemann, Yiqiao Zhang, Claudia Graser, Humeyra Tas, Michael Fleischer, Britta Kaltwasser, Benedikt Frank, , Dirk Matthias Hermann

This study shows that neutralizing extracellular histones reduces secondary brain injury and improves recovery after ischemic stroke complicated by pneumonia.

bioRxiv · Mar 3, 2026 · PreprintNeuroscience

Rapid and fully automated blood vasculature analysis in 3D light-sheet image volumes of different organs

Philippa Spangenberg, Nina Hagemann, Anthony Squire, Nils Förster, Sascha D. Krauß, Yachao Qi, Ayan Mohamud Yusuf, Jing Wang, Anika Grüneboom, Lennart Kowitz, Sebastian Korste, Matthias Totzeck, Zülal Cibir, Ali Ata Tuz, Vikramjeet Singh, , Axel Mosig A

VesselExpress automates 3D blood vasculature analysis in LSFM data, enabling rapid and unbiased quantification of vascular parameters across multiple organs.

Cell Reports Methods · Mar 1, 2023Peer-reviewedBioinformatics

Microbiota-derived short chain fatty acids promote Aβ plaque deposition

Alessio Vittorio Colombo, Rebecca Sadler, Gemma Llovera, Vikramjeet Singh, Stefan Roth, Steffanie Heindl, Laura Sebastián Monasor, Aswin Verhoeven, Finn Peters, Samira Parhizkar, Frits Kamp, Mercedes Gomez de Agüero, Andrew James Macpherson, Edith Winkler, Jochen Wolfgang Herms, , Arthur Liesz

This study shows that microbiota-derived short chain fatty acids (SCFA) increase Aβ plaque deposition in Alzheimer's disease by promoting microglial activation and ApoE upregulation.

eLife · Apr 12, 2021Peer-reviewedNeuroscience

Stroke increases the expression of ACE2, the SARS-CoV-2 binding receptor, in murine lungs

Vikramjeet Singh, Alexander Beer, Andreas Kraus, Felix Mang, Xiaoni Zhang, Jinhua Xue, Nina Hagemann, Dirk Matthias Hermann, Matthias Gunzer

This study shows that experimental stroke in mice increases ACE2 expression and inflammation in the lungs, potentially explaining why stroke patients are at higher risk for severe SARS-CoV-2 infections.

Brain Behavior and Immunity · Feb 21, 2021Peer-reviewedNeuroscience