Author

Vinagolu K. Rajasekhar

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-7364-2675Unclaimed ORCID profile · follow to get notified of new preprints

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Vinagolu K. Rajasekhar1 paper

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

Amanda S. Kim· 1 shared Chao WuiD· 1 shared Cheng Zhang· 1 shared Deniz Ata· 1 shared Ezgi HacisuleymaniD· 1 shared Giuseppe Galleti· 1 shared Hu LiiD· 1 shared HyoKyeong Cha· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Amanda S. Kim

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2 papers

Recent·Most cited

EGR1 Mediates Riluzole-Induced Apoptosis in Osteosarcoma via the Yap/p73-Bax Signaling Axis

Syeda Maryam Azeem, Shraddha ChandThakuri, Pooja Prakash Rao, Tamia Abbasi, Jannae McFarlane, Raisa Munira, Sahanama Porshe, Vinagolu K. Rajasekhar, John H. Healey, Shahana S. Mahajan

This study shows Riluzole induces apoptosis in osteosarcoma by upregulating EGR1, which interacts with Yap/p73 to enhance Bax expression and promote cell death.

bioRxiv · Oct 15, 2025 · PreprintCancer Biology

Aging-dependent dysregulation of EXOSC2 is maintained in cancer as a dependency

Maria Skamagki, Cheng Zhang, Ezgi Hacisuleyman, Giuseppe Galleti, Chao Wu, Vinagolu K. Rajasekhar, HyoKyeong Cha, Deniz Ata, Jongjin Kim, Taylor Weisskittel, Mame Diop, Thiri Aung, Michael Del Latto, Amanda S. Kim, Zhuoning Li, , Kitai Kim

The paper investigates how aging-dependent dysregulation of EXOSC2 affects cellular traits and finds that PPP2R5E, a PP2A phosphatase subunit, is a key target of EXOSC2, with this regulation maintained in stem cells and cancer.

bioRxiv · Apr 4, 2025 · PreprintCell Biology