David A. Prober

The paper identifies a neuron-glia circuit in zebrafish that anticipates hypoxia by integrating behavioral intent and physiological state to prevent internal oxygen depletion.

This study identifies stk32a as a conserved sleep regulator that links neuropeptidergic signaling to sleep homeostasis by suppressing sensory and motor systems in zebrafish and mice.

This study identifies distinct sleep sub-states in larval zebrafish using behavioral data and Hidden Markov Modeling, showing their regulation by neuromodulators and conservation across vertebrates.

The paper identifies QRFP/Pth4 neurons in zebrafish hypothalamus as a novel sleep-promoting population that acts through hindbrain monoaminergic neurons.

This paper introduces three HCR variants that improve sensitivity for detecting low-abundance mRNA targets in challenging tissue environments.

The paper shows norepinephrine induces astroglial purinergic signaling that suppresses behavior through adenosine receptor activation in zebrafish.

The paper shows ketamine suppresses futility-induced passivity in zebrafish by modulating astroglial calcium through norepinephrine signaling.

The paper identifies a neural circuit in zebrafish where neuropeptide VF neurons promote sleep by activating serotonergic raphe nuclei.

The paper identifies a novel zebrafish sleep mutant, dreammist, and shows that disruption of a sodium pump regulator affects sleep duration through altered sodium homeostasis.

The paper identifies increased Hypocretin/Orexin signaling as a genetic basis for sleep loss in Mexican cavefish compared to surface fish.

The paper identifies asymmetric projections of central vestibular neurons in zebrafish and shows how these projections enhance sensory encoding of nose-up stimuli while maintaining gaze stabilization.