Author

Samuel W. Kazer

Broad InstituteORCID 0000-0002-7380-9594Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

José Ordovás-MontañésiD· 2 shared Adam ParkeriD· 1 shared Alan Basset· 1 shared Alan Yi-Hui HsuiD· 1 shared Alex K. ShalekiD· 1 shared Andréane CartieriD· 1 shared Andrew KuoiD· 1 shared Andrew W. NaviaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

José Ordovás-MontañésORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sphingosine 1-phosphate receptor-1 signaling enhances neutrophil survival while suppressing inflammation and bacterial host defense functions

Yueh‐Chien Lin, Takahiro Seno, Alan Yi-Hui Hsu, Andréane Cartier, Andrew Kuo, Michel V. Levesque, Avishek Ghosh, Ingo Fohmann, Victoria A. Blaho, Sylvain Galvani, Reed Crocker, Samuel W. Kazer, José Ordovás-Montañés, Hongbo Robert Luo, Timothy Hla

This study shows that S1PR1 signaling in neutrophils enhances their survival and reduces inflammation but impairs bacterial clearance and protects against lung injury in viral infections.

bioRxiv · Aug 28, 2026 · PreprintImmunology

Impact of variants and vaccination on nasal immunity across three waves of SARS-CoV-2

Jaclyn M. L. Walsh, Vincent N. Miao, Anna H. Owings, Ying Tang, Joshua D. Bromley, Samuel W. Kazer, Kyle Kimler, Chelsea Asare, Carly G.K. Ziegler, Samira Ibrahim, Tasneem Jivanjee, Micayla George, Andrew W. Navia, Riley S. Drake, Adam Parker, , José Ordovás-Montañés

This study examines how SARS-CoV-2 variants and vaccination affect nasal immunity across three waves, identifying changes in cellular states and immune responses.

Nature Immunology · Jan 20, 2025Peer-reviewedImmunology

Constitutive immune surveillance of nasal mucosa by three neutrophil subsets with distinct origin, phenotype, and function

Rodrigo J. Gonzalez, Pavel Hanč, David Álvarez, Samuel W. Kazer, Marie-Angele Messou, Irina B. Mazo, Colette Matysiak, Rohit Garg, Jennifer D. Helble, Paris Pallis, Rachel J. Ende, Alan Basset, Rick Malley, Isabelle Derré, Michael N. Starnbach, Ulrich H. von Andrian

This study identifies three distinct neutrophil subsets in the murine nasal mucosa with unique origins, phenotypes, and functions in immune surveillance.

bioRxiv · Mar 6, 2024 · PreprintImmunology