Isabelle Derré

Intracellular pathogen targeting by IL32 elicits cell-autonomous immunity

The paper identifies IL32 as a cytokine that targets intracellular pathogens via the N-degron pathway and autophagy, revealing a mechanism by which IFN-gamma signaling mediates host defense against pathogens like Chlamydia.

A Microphysiologic Model of the Cervical Epithelium Recapitulates Microbial, Immunologic, and Pathogenic Properties of Sexually Transmitted Infections

This paper develops a microphysiologic model of the cervical epithelium that replicates microbial, immunologic, and pathogenic features of STIs caused by Chlamydia and Neisseria.

Constitutive immune surveillance of nasal mucosa by three neutrophil subsets with distinct origin, phenotype, and function

This study identifies three distinct neutrophil subsets in the murine nasal mucosa with unique origins, phenotypes, and functions in immune surveillance.