Author

Connor Dufort

Boston Children's HospitalORCID 0000-0002-7477-5023Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Adam M. H. Young· 2 shared Alec J. WalkeriD· 2 shared Beth StevensiD· 2 shared Evan Z. MacoskoiD· 2 shared Lasse Dissing‐Olesen· 2 shared Robin J.M. FrankliniD· 2 shared Samuel E. MarshiD· 2 shared Timothy R. HammondiD· 2 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersNeuroscience

Adam M. H. Young

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Single Cell Sequencing Reveals Glial Specific Responses to Tissue Processing & Enzymatic Dissociation in Mice and Humans

Samuel E. Marsh, Alec J. Walker, Tushar Kamath, Lasse Dissing‐Olesen, Timothy R. Hammond, Yvanka de Soysa, Adam M. H. Young, Sarah Murphy, Abdulraouf Abdulraouf, Naeem M. Nadaf, Connor Dufort, Alicia C. Walker, Liliana E. Lucca, Velina Kozareva, Charles R. Vanderburg, , Beth Stevens

The paper shows enzymatic dissociation causes gene expression changes in microglia and proposes a protocol to reduce these artifacts in scRNA-seq.

Nature Neuroscience · Mar 1, 2022Peer-reviewedNeuroscience

Complex cell-state changes revealed by single cell RNA sequencing of 76,149 microglia throughout the mouse lifespan and in the injured brain

Timothy R. Hammond, Connor Dufort, Lasse Dissing‐Olesen, Stefanie Giera, Adam M. H. Young, Alec Wysoker, Alec J. Walker, Frederick W. Gergits, Michael Segel, James C. Nemesh, Samuel E. Marsh, Arpiar B. Saunders, Evan Z. Macosko, Florent Ginhoux, Jinmiao Chen, , Beth Stevens

This study identifies nine distinct microglial states in mice across lifespan and after injury using single-cell RNA sequencing, revealing persistent and age-related changes.

Immunity · Nov 21, 2018Peer-reviewedNeuroscience