C. Daniel Salzman

Lasting aversive consequences of a single dose of 4-hydroxytamoxifen

This study shows that a single dose of 4-hydroxytamoxifen causes aversive effects and identifies brain areas involved in conditioned taste avoidance.

The representational geometry of emotional states in basolateral amygdala

The paper investigates how the basolateral amygdala encodes emotional states through representational geometry, finding that valence and motor responses are encoded in orthogonal directions enabling specialized readouts.

Two-timepoint assays of neural responses increase the sensitivity and specificity of single-cell whole-brain activity screens

This paper introduces a whole-brain screening method using two-timepoint assays to improve sensitivity and specificity in identifying neural responses, validated through studies on hunger, satiety, and semaglutide treatment.

Neural representations supporting generalization under continual learning

The paper develops a factorized model of temporal abstraction to study how abstract knowledge is learned and represented in the brain during a decision task, showing that hippocampus, entorhinal cortex, and orbitofrontal cortex support this process.

Abstract representations emerge in human hippocampal neurons during inference behavior

The paper shows that human hippocampal neurons form abstract, disentangled representations during inferential reasoning tasks, which correlate with inference behavior.

Partitioning variability in animal behavioral videos using semi-supervised variational autoencoders

This paper introduces a video analysis tool that combines supervised pose estimation with unsupervised dimensionality reduction to extract interpretable behavioral features from animal videos, improving downstream analyses.

The geometry of abstraction in hippocampus and prefrontal cortex

The paper examines how neural representations in monkeys and simulated networks encode abstract variables for generalization in decision-making tasks.

Low dimensional dynamics for working memory and time encoding

The paper analyzes neural activity in non-human primates during time delays to understand working memory and time encoding mechanisms, finding that time can be decoded with high precision and neural trajectories are low dimensional.

Prelimbic-dependent activation of amygdala somatostatin interneurons signals non-aversive cues to promote discrimination.

This study shows that prelimbic cortex-dependent activation of basolateral amygdala somatostatin interneurons promotes discrimination of non-threatening stimuli by blocking theta-oscillation phase resetting.