Beatrice S. Knudsen

Comparison of QuPath and HALO platforms for analysis of the tumor microenvironment in prostate cancer

This study compares QuPath and HALO for analyzing prostate cancer tumor microenvironment using multiplex immunofluorescence data, finding high concordance and demonstrating QuPath's flexibility.

Intrinsic higher potency of basal urothelial cells to intermediate and umbrella cells as the cell of origin for bladder cancer

This study identifies basal urothelial cells as the most potent cell of origin for aggressive bladder cancer subtypes, based on lineage tracing and single-cell RNA sequencing in mouse models.

Tenascin-C in the early lung cancer tumor microenvironment promotes progression through integrin activation and FAK

This study shows that Tenascin-C promotes early lung cancer progression by activating integrins and FAK in mouse models and human lung adenocarcinomas.