Hannah Klim

Bovine H5N1 influenza viruses have adapted to more efficiently use receptors abundant in cattle

This study shows bovine H5N1 influenza viruses have adapted to efficiently use NeuGc receptors in cattle, enhancing replication without significantly altering zoonotic risk.

Emerging Haemagglutinin Mutations in Bovine-origin H5N1 Influenza Viruses from Humans and Cattle Retain Avian Receptor Binding with Increased Stability

This study examines HA mutations in bovine-origin H5N1 influenza viruses, finding they retain avian receptor binding but show increased HA stability, potentially raising zoonotic risk.

Mutations in severe human H5N1 cases facilitate evasion from human mucus and antivirals

This study examines mutations in H5N1 influenza virus HA that affect receptor binding and antiviral susceptibility, finding reduced sialic acid binding correlates with mucus evasion and antiviral resistance.