Paul M. Magwene

Meiosis-specific genes play roles in ploidy reduction in Cryptococcus neoformans titan cells

This study identifies meiosis-specific genes critical for ploidy reduction in Cryptococcus neoformans titan cells, showing their role in generating stable diploid daughter cells.

WeavePop: A bioinformatics workflow to explore and analyze genomic variants of eukaryotic populations

WeavePop is a Snakemake workflow for analyzing genomic variants in eukaryotic populations, providing a reproducible and scalable solution with a web interface for variant discovery.

Temperature and genetic background drive mobilization of diverse transposable elements in a global human fungal pathogen

This study shows that temperature and genetic background influence transposable element (TE) mobilization in Cryptococcus neoformans, increasing antifungal resistance and genomic changes.

Distinct evolutionary trajectories following loss of RNA interference in Cryptococcus neoformans

The paper identifies RNAi loss-of-function mutations in Cryptococcus neoformans and shows they can lead to hypermutation when combined with transposon burdens.

Amoeba Predation of Cryptococcus: A Quantitative and Population Genomic Evaluation of the Accidental Pathogen Hypothesis

The paper tests the accidental pathogen hypothesis by identifying a QTL linked to amoeba resistance and melanization in Cryptococcus species, finding no correlation with macrophage resistance or virulence.

Core gene set of the species Saccharomyces cerevisiae

The paper identifies the core gene set of Saccharomyces cerevisiae by analyzing 94 strains, revealing 5885 core genes and highlighting annotation issues and genomic variability.

Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen

This study identifies genetic interactions governing morphogenesis in Cryptococcus fungi using QTL analysis, revealing epistatic relationships between genes involved in signaling pathways.

Pleiotropy and Epistasis Within and Between Signaling Pathways Defines the Genetic Architecture of Fungal Virulence

This paper identifies genetic loci and pathways underlying virulence traits in Cryptococcus deneoformans using QTL mapping and finds that key signaling pathways contribute to phenotypic variation.

A High Resolution Map of Meiotic Recombination in Cryptococcus Demonstrates Decreased Recombination in Unisexual Reproduction

The paper maps meiotic recombination in Cryptococcus deneoformans, finding lower recombination rates in unisexual reproduction compared to bisexual crosses.

Private haplotype barcoding facilitates inexpensive high-resolution genotyping of multiparent crosses

The paper introduces a method called private haplotype barcoding to reduce costs of genotyping offspring from multiple crosses by pooling samples and using haplotype information for deconvolution.