Author

Maftuna Shamshiddinova

University Hospital Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:metabolomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam Majcher· 2 shared Elkhan YusifoviD· 2 shared Thorsten HornemanniD· 2 shared Andreas J. HülsmeieriD· 1 shared Christoph ArenziD· 1 shared Ermanno MalagolaiD· 1 shared Essa M. SaiediD· 1 shared Gai Zhibo· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Adam Majcher

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

CYP4F2-mediated ω-hydroxylation of 1-deoxysphingolipids reveals a new hepatic detoxification pathway

Adam Majcher, Essa M. Saied, Zoltán Kutalik, Maftuna Shamshiddinova, Andreas J. Hülsmeier, Par Bjorklund, Elkhan Yusifov, Irina Alecu, Christoph Arenz, Thorsten Hornemann

This study identifies CYP4F2 as a key enzyme mediating ω-hydroxylation of 1-deoxySLs, revealing a new hepatic detoxification pathway that reduces their cytotoxicity.

bioRxiv · May 14, 2026 · PreprintBiochemistry

Very long chain fatty acids drive 1-deoxy-Sphingolipid toxicity

Adam Majcher, Gergely Karsai, Elkhan Yusifov, Martina Schaettin, Ermanno Malagola, Péter Horváth, Jinmei Li, Maftuna Shamshiddinova, Gai Zhibo, Raghvendra Dubey, Timothy R. Peterson, Sofía Rodriguez-Gallardo, Kuniyoshi Shimizu, 武士原山, Thorsten Hornemann

This study identifies VLC fatty acids as mediators of 1-deoxySL toxicity through mitochondrial dysfunction and BAX-dependent apoptosis.

bioRxiv · May 13, 2025 · PreprintBiochemistry